Dr Markus Wilken

I am a lecturer in the Department of Biochemistry, Genetics, and Microbiology at the University of Pretoria, specializing in the molecular biology of plant pathogenic fungi. My research employs genomics and molecular tools to investigate the fundamental biology of these organisms, particularly those affecting South Africa’s commercial forestry and agricultural sectors. The goal of my work is to enhance our understanding of these pathogens within the South African context while addressing questions of global importance.

Sexual Reproduction in the Ceratocystidaceae

Building upon my postdoctoral work, I am engaged in an ongoing study of the mating systems within the Ceratocystidaceae family. This research aims to elucidate the evolutionary history of sexual reproduction in these fungi by examining their mating-type loci and pheromone/receptor systems. The genomic data generated not only advance our understanding of their reproductive strategies but also provide valuable resources that underpin various studies on the biology and pathogenicity of Ceratocystidaceae species.

Grain Research Project at FABI

As a member of the Grain Research Programme (GRP) at the Forestry and Agricultural Biotechnology Institute (FABI), I contribute to research supporting South Africa’s agricultural sector. My focus is on Sclerotinia sclerotiorum, a multihost pathogen of significant economic importance. Despite the extensive global literature on this fungus, its behavior and impact within Southern Africa remain underexplored. Through genomic and molecular studies, I aim to improve our understanding of S. sclerotiorum in the region, thereby informing more effective disease management strategies.

Expanding Genomics Approaches to Additional Plant Pathogens

In addition to my work on the Ceratocystidaceae and Sclerotinia sclerotiorum, I have broadened my research to include other economically important plant pathogenic fungi. By applying similar genomic and molecular biology techniques, I have contributed to studies that provide draft genome sequences and preliminary analyses for several economically important species. This expanded approach not only deepens our understanding of the genetic basis of fungal pathogenicity but also supports the development of targeted strategies to mitigate the impact of these pathogens on both forestry and agricultural systems.